Traditional market access practices are being transformed by an increasingly rocky landscape of rebate, discount, and direct-distribution practices, but artificial intelligence may clear the pathways to profitability.

The Key to Connecting with Patients: Pharma's Market Access Transformation

How pharma can productively coexist with PBMs—and still lower drug costs faster.

Working with the Middle

As safety data grows in scale and complexity, AI-powered pharmacovigilance is emerging as a strategic imperative—helping drugmakers improve detection, reduce risk, and strengthen commercial performance.

The Next Era of Drug Safety is in Intelligent Action

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Pharmaceutical Commerce - December 2025

Articles

Policy shifts bring meaningful improvements for some—but looming coverage losses and rising premiums threaten to erase those gains.

What Does Healthcare Look Like for Patients in 2026?

. He can be reached at nsaraceno@mjhlifesciences.com.

A landmark FTC settlement requires Express Scripts to overhaul formulary and rebate practices, boosting price transparency in the process. 

FTC–Express Scripts Settlement Targets PBM Rebates, Transparency, and Patient Drug Costs

CMS’s Globe and Guard models extend MFN pricing into Medicare Part B and Part D, signaling a sweeping shift in US drug pricing policy.

Flood the Zone with Generous, Globe, and Guard

At Trade & Channel Strategies, industry executives explored evolving channel models, serialization challenges, generics and biosimilars, and the strategies shaping pharma's future.

Why Adaptive Capacity May Define Long-Term Success

Podcasts

In today’s Pharma Pulse, the biopharma landscape enters a transformative phase as the US signs landmark PBM reforms into law, while Novartis braces for the largest patent expiration cycle in its history.

Pharma Pulse: Transparency Mandates and the Novartis Patent Storm

By unifying data, workflows, and decision-making across partners, AI orchestration is enabling healthcare supply chains to move from reactive firefighting to proactive resilience—supporting faster responses, smarter tradeoffs, and more reliable patient care delivery.

How AI Orchestration Is Reinventing Healthcare Supply Chain Resilience

Videos

In the final part of his Pharma Commerce video interview, Joe Hudicka, entrepreneur and supply chain expert, outlines how real-time AI signal sharing across supply chain partners can help pharma companies anticipate demand shifts, reduce shortages, and respond faster to pandemics and geopolitical disruptions.

How AI Ecosystems Could Transform Pharma Demand and Crisis Response

In today’s Pharma Pulse, AstraZeneca faces a complete response letter for its self-injectable lupus drug, while the EMA gives the green light to a historic wave of new therapies for MASH, rare diseases, and postmenopause.

Pharma Pulse: AstraZeneca’s US Setback and Europe’s Medicine Marathon

The acquisition expands ORBIS’ manufacturing capacity and technical expertise in reusable plastic pallets, lids, and trays, enabling faster design, prototyping, and production for pharma and broader supply chain applications.

ORBIS Acquires Robinson Industries to Boost Reusable Packaging and Thermoforming Capabilities

In the third part of his Pharma Commerce video interview, Joe Hudicka, entrepreneur and supply chain expert, explains why independent verification, validation, and human decision-making must stay central, as AI accelerates data processing and operational workflows across pharma supply chains.

Featured Content

The Key to Connecting with Patients: Pharma's Market Access Transformation

Working with the Middle

The Next Era of Drug Safety is in Intelligent Action

Pharmaceutical Commerce - December 2025