Pharma Pulse: Measles Vaccination Gaps Persist, FDA Approves Guselkumab for Children, and AbbVie Expands US Manufacturing

September 30, 2025
Nicholas Saraceno, Editor

Nicholas Saraceno is Editor of Pharmaceutical Commerce. He can be reached at nsaraceno@mjhlifesciences.com.

This episode of Pharma Pulse covers new data showing measles vaccine coverage remains below herd immunity thresholds, the FDA’s approval of guselkumab for pediatric plaque psoriasis and psoriatic arthritis, and AbbVie breaking ground on a new API manufacturing site in Illinois.

Welcome to Pharma Pulse, a Pharmaceutical Commerce podcast where we bring you the latest insights shaping patient access, supply chain/logistics, data & tech, and healthcare innovation. I’m your host, and today we’re looking at concerning measles vaccination trends, a key FDA approval in pediatric dermatology, and AbbVie’s latest investment in US manufacturing.

  • New data show that measles vaccination rates remain well below the herd immunity threshold, raising concerns about the risk of outbreaks. Public health officials warn that coverage gaps are leaving communities vulnerable to a disease that had once been nearly eliminated in the United States. Experts point to misinformation, access challenges, and vaccine fatigue as contributing factors, and are calling for stronger outreach to boost immunization rates.
  • In regulatory news, the FDA has approved guselkumab for children ages six and older with moderate-to-severe plaque psoriasis or active psoriatic arthritis. This marks the first approval of an IL-23 inhibitor for pediatric patients in these conditions. Clinical trial results showed significant improvements in skin clearance and symptom control, giving families and providers an important new treatment option.
  • Lastly, in manufacturing, AbbVie has broken ground on a new active pharmaceutical ingredient facility in Illinois. The $200 million-plus project is designed to expand domestic production capacity and support AbbVie’s growing pipeline. Company leaders say the site will play a key role in strengthening supply chain resilience and ensuring reliable access to critical therapies.

From lagging measles vaccine coverage to new pediatric treatment approvals and major investments in US manufacturing, these stories underscore the mix of challenges and progress shaping pharma today.

That’s it for this episode of Pharma Pulse. For more insights on trends transforming pharmaceutical access and care delivery, visit pharmaceuticalcommerce.com.

Thanks for listening—until next time, stay well and stay informed.

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